Subject of the article

Authors

Radjabov J.P.

Institution

Samarkand State Medical University

Abstract

The clinical study included 371 patients with liver echinococcosis. Optimization of the tactics of surgical treatment of liver echinococcosis, taking into account the choice of access, method of treatment and elimination of the residual cavity, as well as correction of the course of prophylactic chemotherapy, improved the quality of care by reducing the frequency of immediate postoperative complications from 12.5% to 4.3% and the recurrence of the disease from 11.9% to 2.6%. It is clini-cally justified to correct the dose of albendazole for the prevention of recurrence of liver echinococ-cosis in patients with concomitant chronic diffuse liver pathology, which made it possible to reduce the likelihood of adverse reactions from 52.7% to 18.3%, and, accordingly, indicators of hepatic ami-notransferases: ALT in the comparison group from 1.14± 0.11 to 0.62±0.05 mmol/l in the main group and AST from 0.72±0.07 to 0.52±0.04 mmol/l.

Key words

liver echinococcosis, surgical treatment, chemotherapy.

Literature

1. Anteplı̇oğlu T. et al. Assessment of oxidative stress and tissue damage in Echinococcus granulosus naturally infected bovine liver //Tissue and Cell. – 2024. – Т. 87. – С. 102333.
2. Nazyrov F. G. et al. Шляхи покращення результатів хірургічного лікування ехінококкоза печінки //Неонатологія, хірургія та перинатальна медицина. – 2018. – Т. 8. – №. 3 (29). – С. 39-43.
3. Shamsiev A. M. et al. Differentiated treatment tactics in surgery of liver echinococcosis //Experimental and Clinical Gastroenterology. – 2020. – Т. 174. – №. 5. – С. 72-77.
4. Shamsiev A. M. et al. Эхинококкоз печени: частота встречаемости, патогенез, классификация, диагностика и лечение (обзор литературы) //Клінічна та експериментальна патологія. – 2018. – Т. 17. – №. 3.
5. Shamsiyev A. M. et al. Development of surgical treatment of echinococcosis of the liver (literature review) // Modern innovations: current directions of scientific research. – 2017. – С. 45-49.
6. Zarifovich K. B. et al. Лазерная фотодинамическая терапия как метод обработки остаточной полости после эхинококкэктомии печени //Journal of biomedicine and practice. – 2022. – Т. 7. – №. 4