Bulletin of fundamental and clinic medicine , 2024, №6 (12)

Subject of the article

THE STATE OF THE IMMUNE STATUS IN PATIENTS INFECTED WITH COVID-19 WITH ACUTE RHINOSINUSITIS (52-59)

Authors

Narzullaev N.U.

Institution

Bukhara State Medical Institute

Abstract

The immune status has been studied at 25 COVID-19 of patients with ARS. The control group of comparison consisted from 14 practically healthy faces. At a HIV-infected of patients with ARS has revealed deep infringements of the immune status, especially from the T-link of immunity and its subpopulations, and also frustration humoral an immunity link, suppression of proinflammatory cytokine IL-10 and increase proinflammatory IFN-γ. Under the influence of the spent treatment have not revealed certain changes from the immune status at patients. It is possible to ascertai

Key words

The immune status, COVID-19, acute rhinosinusitis, cellular immunity, humoral immunity, an immunodeficiency, cytokines.

Literature

  1. Aripova T.U., Ismailova A.A. COVID-19: possibilities of immunotherapy : review / // Journal of Theoretical and Clinical Medicine : scientific and practical medical journal / Academy of Sciences of the Republic of Uzbekistan. - Tashkent : Institute of Immunology of the Academy of Sciences of the Republic of Uzbekistan. - 2020. - No. 3. - Р. 8-12.
  2. Assanovich M.A. Escitalopram in pharmacotherapy of mental disorders in patients with COVID-19 //Medical news. 2021. No. 1 (316). - pp. 59-62.
  3. Bazdyrev E.D. Coronavirus infection - an urgent problem of the XXI century //Complex problems of cardiovascular diseases. 2020. Vol. 9. No. 2. - pp. 6-16.
  4. Bachilo E.V. Mental health of the population during the COVID-19 pandemic //Journal of Neurology and Psychiatry named after C.C. Korsakov. 2020. Vol. 120. No. 10.- pp. 130-136.
  5. Bekzhanova O.E., Kayumova V.R., Alimova S.H. Clinical and pathogenetic aspects of olfaction and taste disorders in COVID-19.Tashkent State Dental Institute-2021.-pp.67-74.
  6. Belyakov N.A., Rassokhin V.V., Yastrebova E.B. Coronavirus infection COVID-19. the nature of the virus, pathogenesis, clinical manifestations. message 1 //HIV infection and immunosuppression. 2020. Vol. 12. No. 1. - pp. 7-21.
  7. Demyanov A.V. V. et al. diagnostic value of the study of cytokine levels in clinical practice. // Cytokines and inflammation. - 2003 No. 3. – pp. 20-23.
  8. Lantsov A.A., Khmelnitskaya N.M., Endaltseva E.B. Local immunity and treatment of patients with chronic purulent otitis media // News of otorhinolaryngology and logopathology. -1999. – No. 1. – pp. 3-7.
  9. Narzulaev N.U., Khamidova N.K., Mirzayeva M.R. Clinical and immunological study of the effect of various types of therapy on the course of allergic rhinitis in children with hymenolepidosis// Annals of the Romanian Society of Cell Biology 2021. pp. 1900-1908.
  10. Narzulaev N.U., Mirzayeva M.R. Immunological features of infectious mononucleosis Epstein-Barr virus etiology in children// International Journal of Pharmaceutical Research 2021, pp 2667-2671.
  11. Narzullaev N.U., Rakhmatov A.A. Cytokine profile in children with acute inflammation of the middle earth on the background of chronic active hepatitis // Tibbietda yangi kun. No. 2 (34). Tashkent 2021, pp.15-17.

ARTICLES