Subject of the article

Authors

Tursunov F.U., Isakulova M.M., Kodirova M.Zh., Irmamativa Z.A.

Institution

Samarkand State Medical University, Samarkand, Uzbekistan

Abstract

Anemia is a common pathology in elderly patients that significantly affects quality of life. The aim of our study is to evaluate the age-related clinical and laboratory features of anemia in individuals aged 60–74 and 75 years and older. The study included 60 patients with anemia divided into two age groups. A comprehensive set of laboratory tests was performed: complete blood count, iron, ferritin, vitamin B12, C reactive protein, and others. Significant differences in types and severity of anemia between groups were identified, emphasizing the need for an individualized approach to diagnosis and therapy. The study results may be useful for clinical practice of geriatricians and laboratory specialists.

Key words

anemia, elderly patients, laboratory diagnosis, hemoglobin, ferritin, vitamin B12, inflam mation, age-related features, therapy monitoring

Literature

1.Guralnik JM, Eisenstaedt RS, Ferrucci L, Klein HG, Woodman RC. Prevalence of anemia in persons 65 years and older in the United States: evi dence for a high rate of unexplained anemia. Blood. 2004;104(8):2263-2268. 2.Patel KV. Epidemiology of anemia in older adults. Semin Hematol. 2008;45(4):210-217. 3.Goodnough LT, Schrier SL. Evaluation and management of anemia in the elderly. Am J Hema tol. 2014;89(1):88-96. 4.Thomas DR. Anemia in the elderly. Am J Clin Nutr. 2001;73(4):575-578. 5.Artz AS, Thirman MJ. Anemia in the elder ly. Curr Opin Hematol. 2010;17(3):198-203. 6.Andrès E, Serraj K, Noel E, et al. Anemia of chronic disease in the elderly. Eur J Intern Med. 2008;19(2):88-92. 7.Price EA, Mehra R, Holmes TH, Schrier SL. Anemia in older persons: etiology and evaluation. Blood Cells Mol Dis. 2011;46(2):159-165. 8.Carmel R. Vitamin B12 deficiency. N Engl J Med. 2012;368(2):149-160. 9.Short MW, Domagalski JE. Iron deficiency anemia: evaluation and management. Am Fam Phy sician. 2013;87(2):98-104. 10.Weiss G, Goodnough LT. Anemia of chronic disease. N Engl J Med. 2005;352(10):1011 1023. 11.Culleton BF, Manns BJ, Zhang J, et al. Impact of anemia on hospitalization and mortality in older adults. Blood. 2006;107(10):3841-3846. 12.Penrod JD, Litke A, Laporte A, D’Agostino RB Sr, Feinberg B, Deyo RA. Clinical and economic outcomes of anemia in older adults. Arch Intern Med. 2004;164(14):1530-1537. 13.Gaskell H, Derry S, Moore RA, McQuay HJ. Prevalence of anemia in older persons: systemat ic review. BMC Geriatr. 2008;8:1.