Bulletin of fundamental and clinic medicine 2025, №3 (17)
Subject of the article
COMPARATIVE ASSESSMENT OF MORPHOMETRIC PARAMETERS OF HYPERTROPHYING PHARYNGEAL TONSILS IN AGE ASPECT (37-42)
Authors
Alimova N.P., Khasanovа D.A.
Institution
Bukhara State Medical Institute named after Abu Ali ibn Sino, Bukhara, Uzbekistan
Abstract
The aim of this work was to study the age-related features of the adenoid tissue structure. The study included a histological analysis of the removed adenoid tissue in children who underwent surgical treatment of adenoid growths. In patients of the first age group, the tissue structure indicated adaptive changes in the local immune system to external influences and the formation of a respiratory immune barrier - the phase of formation of a local immune response. In children of the second group, a weakening of the barrier function of the epithelium was observed, caused by focal squamous cell metaplasia, as well as signs of chronic inflammation with an active reaction of the lymphoid tissue and a pronounced immune response. In children of the third group, persistence of microbial agents in the crypts and the presence of inflammatory cells were detected, which indicated chronic inflammation against the background of depletion of the local lymphoid apparatus. Thus, changes in the adenoid tissue are considered as a manifestation of a local im mune response to the influence of external factors.
Key words
adenoids, lymphoid tissue, age-related changes, morphology
Literature
- Биология полости рта. Под ред. Е.В. Бо ровского, В.К. Леонтьева. - М.: Медицина 2001; 304. adenotonsillectomy. Int J Pediatr Otorhinola-ryngol 2004; 68 (3): 311-316.
- Быков В.Л. Гистология и эмбриология органов полости рта человека: учеб. пособие. 2-е изд., испр. СПб.: Спец. лит-ра 1998; 248.
- Быкова В.П., Калинин Д.В. Состояние глоточной миндалины часто болеющих детей после местной иммуномодулирующей терапии. Российская ринология 2011; 3.
- Marques V.C., Anselmo-LimаT. Pre and postoperative evaluation by acoustic rhino metry of children submitted to adenoidectomy or
- Mohn K.G.I., Bredholt G., Brokstad K.A., Pathirana R.D.H.J. Aarstad C., Tondel R.J., Cox, Longevity of B-Cell and T-Cell Responses After Live Attenuated Influenza Vaccination in Children, Journal of Infectious Diseases, 10.1093/infdis/jiu654, 211, 10, (1541-1549), 2014.
- Nasrin M, Miah M.R., Datta P.G., Saleh A.A., Anwar S., Saha K.L. Effect of tonsillectomy on humoral immunity. Bangladesh Med Res Counc Bull. 2012. 38(2): 59-61.
