Bulletin of fundamental and clinic medicine 2025, №3 (17)

Subject of the article

USE OF PROGESTERONE IN PRETERM BIRTH PREVENTION IN WOMEN WITH A “SHORT” CERVIX (87-90)

Authors

Goyibov S.S., Abduvalieva N.B.

Institution

Samarkand State Medical University, Samarkand, Uzbekistan

Abstract

Premature birth is one of the important problems of modern obstetrics and is one of the main causes of perinatal morbidity and mortality. Two thirds of premature births occur with spontaneous onset of labor. Spontaneous premature birth is a syndrome of cervical ripening caused by a decrease in the effect of progesterone. Ultrasound of the cervix, performed in the second half of pregnancy, is the main prognostic criterion for spontaneous premature birth. Numerous studies have shown that the use of vaginal progester one before 33 weeks of pregnancy reduces the risk of preterm birth by up to 42% and reduces the need for intensive care, respiratory distress syndrome, the need for artificial respiration, and neonatal mortality. The use of ultrasound in the diagnosis of short cervix in preterm labor, as well as the use of vaginal progesterone in women with a short cervix, are both cost-effective and efficient, which led to the need for this practice.

Key words

vaginal progesterone, preterm birth, cervical sutures.

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