Фундаментал ва клиник тиббиёт ахборотномаси, 2026, №1 (21)

Maqola mavzusi

THE SIGNIFICANCE OF DRIVER GENE MUTATIONS JAK2, CALR, AND MPL IN CHRONIC MYELOPROLIFERATIVE DISEASES (159–163)

Mualliflar

Giyosov B.B., Boboev K.T., Daminov F.A.

Muassasa

1-Samarkand State Medical University, Samarkand, Uzbekistan 2-Republican Specialized Scientific-Practical Medical Center of Hematology, Tashkent, Uzbekistan

Annotatsiya

Driver mutations in the JAK2, CALR, and MPL genes play a crucial role in the diagnosis of myeloproliferative disorders, enabling accurate identification of their type and exclusion of other diseases with similar symptoms. Purpose. To determine the role of driver gene mutations (JAK2, CALR, and MPL) in chronic myeloproliferative neoplasms (MPNs), including their significance in pathogenesis, diagnosis, and clinical management.

Kalit so'zlar

Myeloproliferative diseases, diagnosis, driver genes: JAK2, CALR, MPL

Adabiyotlar

MAQOLALAR

JURNAL SONLARI