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Mualliflar

Rajabov H.R., Karimov R.X.

Muassasa

Urgench State Medical Institute, Khorezm Regional Center of Eye Microsurgery, Urgench, Uzbekistan

Annotatsiya

Pterygium is a degenerative–proliferative ocular surface disorder characterized by fibrovascular tissue growth onto the cornea and a high rate of postoperative recurrence. Despite advances in surgical management, recurrence remains a major clinical challenge, underscoring the importance of detailed morphometric evaluation of pterygium tissue.To investigate and compare the morphometric characteristics of fibrovascular tissue components in different morphological variants of pterygium and to assess their potential clinical significance. This retrospective morphometric study included biopsy specimens from 78 patients surgically treated for pterygium at the Khorezm Regional Center of Eye Microsurgery between 2022 and 2024. Histological sections were stained with hematoxylin and eosin and digitized using a NanoZoomer scanner. Quantitative morphometric analysis was performed with QuPath-0.5.0 software. The assessed parameters included the area occupied by fibroblasts, collagen fibers, blood vessels, inflammatory infiltrates, and interstitial tissue. Statistical analysis was conducted using variation statistics, with significance set at P < 0.05.

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