Bulletin of fundamental and clinic medicine, 2022 №5
Subject of the article
CLINICAL AND MORPHOLOGICAL CHARACTERISTICS OF OUT-OF-HOSPITAL PNEUMONIA COMBINED WITH GASTROESOPHAGEAL REFLUX DISEASE (127-132)
Authors
Bisov A.S. , Pobedyonnaya G.P. , Kozitskaia I.V.
Institution
FSBEE HE “Lugansk State Medical University named after St. Luke's" Ministry of Health of Russia FSBEE HE “Lugansk State Medical University named after St. Luke's" Ministry of Health of Russia GU "LRKB MMC" LNR
Abstract
The clinical course of out–of-hospital pneumonia (P) combined with gastroesophageal reflux disease (GERD) was studied in 67 patients, including P with GERD - 38 people, P without GERD – 29 patients. It was revealed that in patients with P combined with GERD, there is a more severe course of P than in patients without GERD and is supplemented by a greater frequency of asthenic syndrome, extraesophageal and esophageal manifestations of GERD. In patients with P combined with GERD, the frequency of respiratory extraesophageal manifestations increases, which, compared with patients with P without GERD, aggravates the manifestations of respiratory syndrome. The CRP index in patients with P combined with GERD is detected 1.3 times higher than in patients with P without GERD, which reflects a higher level of systemic inflammation in comorbid pathology and implies a greater amount of therapeutic efforts.
Key words
community-acquired pneumonia, GERD.
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