MORPHOFUNCTIONAL CHANGE OF RAT THYMUS DURING CHRONIC IRRADIATION

Bulletin of fundamental and clinic medicine, 2022 №5

Subject of the article

MORPHOFUNCTIONAL CHANGE OF RAT THYMUS DURING CHRONIC IRRADIATION (72-77)

Authors

Asadova Nigora Кhamroyevna

Institution

Bukhara State Medical Institute

Abstract

The study was conducted on 64 white, mongrel 6-monthold rats. The results of the study of the morphometry of the thymus showed that in postnatal ontogenesis their average mass, size, thickness of layers varied differently. The volume of the thymus, length, perimeter and thickness of thymocytes varies unevenly depending on age. In rats with chronic radiation exposure, the growth rate of these parameters is slowed down in comparison with the control group. Chronic radiation sickness negatively affected the number and size of the Ghassal body and led to a decrease in the number of T – lymphocytes and a delay in their maturation rate.

Key words

thymus, Gassal's corpuscles, T-lymphocytes.

Literature

  1. Кирьянов Н.А. [и др.] / Морфологическая характеристика органов иммунной и эндокринной систем при эндотоксикозе// Медицинский вестник Башкортостана. 2013. Т. 8, № 6. С. 156–158.
  2. Михайленко A.A. [и др.]. Профилактическая иммунология / Москва–Тверь: ООО Изд.«Триада». 2004. 448 с.
  3. Сафонова, В. А. Возрастные изменения амилазной актив- ности в тонком отделе кишечника бройлеров / В. А. Сафо- нова, А. М. Пастухов // Матер. науч.-координац. совеща- ния. Казань, 1983. С. 36– 37
  4. Ярилин А. А. /Цитокины в тимусе. Биологическая активность и функции цитокинов в тимусе / А.А. Ярилин // Цитокины и воспаление. 2003. Т. 2, № 2. С. 3–11.
  5. Асадова, Н. Х. (2021). Морфофункциональные Свойства Тимуса И Изменения Действия Биостимуляторов При Радиационной Болезни. CENTRAL ASIAN JOURNAL OF MEDICAL AND NATURAL SCIENCES, 276-279.
  6. Асадова, Н. Х., & Алимова, Н. П. (2022). Сравнителный Анализ Гистопатологии Тимуса Как Централный Орган Иммуной Системы. CENTRAL ASIAN JOURNAL OF MEDICAL AND NATURAL SCIENCES, 3(3), 112-120.
  7. Khasanova, D. A., & Asadova, N. K. (2021). Morpho functional changes in thymus of white rats in acute stress. Academicia: An international multidisciplinary research journal, 11(1), 685-691.
  8. Farxodovna, X. M. (2022). Comparative Analysis of the Morphofunctional State of the Fetoplacental System in Obese Pregnant Women. INTERNATIONAL JOURNAL OF HEALTH SYSTEMS AND MEDICAL SCIENCES, 1(5), 27-30.
  9. Farxodovna, X. M. (2022). Morphological Features of the Structure of the Fetoplacental System in Pregnant Women against the Background of Obesity. Research Journal of Trauma and Disability Studies, 1(9), 100-104

ARTICLES