EXPERIMENTAL DARK DEPRIVATION AS A FACTOR AFFECTING THE WEIGHT AND CRANIOCAUDAL SIZE OF EMBRYOS OF MUSEID RODENTS

Bulletin of fundamental and clinic medicine, 2022 №6

Subject of the article

EXPERIMENTAL DARK DEPRIVATION AS A FACTOR AFFECTING THE WEIGHT AND CRANIOCAUDAL SIZE OF EMBRYOS OF MUSEID RODENTS (9-14)

Authors

Pashinskaya E.S. , Sobolevskaya I.S. , Chicherova K.A. , Yashkina A.V.

Institution

Educational institution «Vitebsk State Order of Peoples' Friendship Medical University»

Abstract

The purpose of the study was to study the effect of experimental dark deprivation on the weight and craniocaudal size of female rat embryos. To set up the experiment, 60 female Wistar rats weighing 180-200 g were used. Experimental animals were randomly divided into 2 groups: control group - 30 female rats under standard fixed lighting conditions (12 hours light/12 hours darkness), experimental group – 30 female rats, animals with simulated dark deprivation under conditions of round-the-clock lighting (24 hours light). In female rats, the total number of embryos, the number of living embryos was counted, their weight and craniocaudal size were measured, and the results were subsequently recorded. A litter data from one female was taken as a unit of observation. The study revealed that chronodestruction caused by dark deprivation contributes to a decrease in the number of living embryos, a decrease in the average weight and average craniocaudal size of embryos at all periods of observation, compared with the control group.

Key words

rats, pregnancy, weight, craniocaudal size, circadian rhythms, dark deprivation.

Literature

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